The vision loss in this condition results from a gradual deterioration of light-sensing cells in the tissue at the back of the eye that detects light and color ( the retina ). Distorted vision and vision loss usually become noticeable in a person's sixties or seventies and tend to worsen over time.Īge-related macular degeneration mainly affects central vision, which is needed for detailed tasks such as reading, driving, and recognizing faces. Subtle abnormalities indicating changes in vision may occur in a person's forties or fifties. Age-related macular degeneration is an eye disease that is a leading cause of vision loss in older people in developed countries.